Advances in our understanding of the pathogenesis of HIV-1 associated nephropathy in children. Full Text

Ray PE, Hu CA.

Future Virol. 2011 Jul;6(7):883-894.


Alterations in the transcriptome and antibiotic susceptibility of Staphylococcus aureus grown in the presence of diclofenac. Full Text

Riordan JT, Dupre JM, Cantore-Matyi SA, Kumar-Singh A, Song Y, Zaman S, Horan S, Helal NS, Nagarajan V, Elasri MO,Wilkinson BJ, Gustafson JE.

Ann Clin Microbiol Antimicrob. 2011 Jul 21;10:30. doi: 10.1186/1476-0711-10-30.


A novel indium-111-labeled gonadotropin-releasing hormone peptide for human prostate cancer imaging. Full Text

Guo H, Gallazzi F, Sklar LA, Miao Y.

Bioorg Med Chem Lett. 2011 Sep 15;21(18):5184-7. doi: 10.1016/j.bmcl.2011.07.055. Epub 2011 Jul 23


Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis. Full Text

Magedov IV, Frolova L, Manpadi M, Bhoga Ud, Tang H, Evdokimov NM, George O, Georgiou KH, Renner S, Getlik M, Kinnibrugh TL, Fernandes MA, Van slambrouck S, Steelant WF, Shuster CB, Rogelj S, van Otterlo WA, Kornienko A.

J Med Chem. 2011 Jun 23;54(12):4234-46. doi: 10.1021/jm200410r. Epub 2011 May 26.


Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells. Full Text

Zhaorigetu S, Yang Z, Toma I, McCaffrey TA, Hu CA.

J Biol Chem. 2011 Aug 5;286(31):27389-98. doi: 10.1074/jbc.M110.210245. Epub 2011 Jun 6.


Aryliodine (III) Diacetates as Substrates for Pd-Ag Catalyzed Arylation of Alkenes. Full Text

Evdokimov NM, Kornienko A, Magedov IV.

Tetrahedron Lett. 2011 Aug 17;52(33):4327-4329.


Breast field cancerization: isolation and comparison of telomerase-expressing cells in tumor and tumor adjacent, histologically normal breast tissue. Full Text

Trujillo KA, Hines WC, Vargas KM, Jones AC, Joste NE, Bisoffi M, Griffith JK.

Mol Cancer Res. 2011 Sep;9(9):1209-21. doi: 10.1158/1541-7786.MCR-10-0424. Epub 2011 Jul 20.


Carrier testing for severe childhood recessive diseases by next-generation sequencing. Full Text

Bell CJ, Dinwiddie DL, Miller NA, Hateley SL, Ganusova EE, Mudge J, Langley RJ, Zhang L, Lee CC, Schilkey FD, Sheth V,Woodward JE, Peckham HE, Schroth GP, Kim RW, Kingsmore SF.

Sci Transl Med. 2011 Jan 12;3(65):65ra4. doi: 10.1126/scitranslmed.3001756.


Cloning and Molecular Analysis of a Mannitol Operon of Phosphoenolpyruvate-dependent Phosphotransferase (PTS) type From Vibrio cholerae O395. Full Text

Sanath Kumar, Kenneth P. Smith, Jody L. Floyd, and Manuel F. Varela

Arch Microbiol. 2011 March; 193(3): 201–208.


Conserved and variable structural elements in the 5' untranslated region of two hypoviruses from the filamentous fungus Cryphonectria parasitica. Full Text

Mu R, Romero TA, Hanley KA, Dawe AL.

Virus Res. 2011 Nov;161(2):203-8. doi: 10.1016/j.virusres.2011.07.023. Epub 2011 Aug 22.


Dairy farm age and resistance to antimicrobial agents in Escherichia coli isolated from dairy topsoil. Full Text

Jones SE, Burgos JM, Lutnesky MM, Sena JA, Kumar S, Jones LM, Varela MF.

Curr Microbiol. 2011 Apr;62(4):1139-46. doi: 10.1007/s00284-010-9839-3. Epub 2010 Dec 12.


Design and synthesis of a new class of membrane-permeable triazaborolopyridinium fluorescent probes. Full Text

Hapuarachchige S, Montaño G, Ramesh C, Rodriguez D, Henson LH, Williams CC, Kadavakkollu S, Johnson DL, Shuster CB,Arterburn JB.

J Am Chem Soc. 2011 May 4;133(17):6780-90. doi: 10.1021/ja2005175. Epub 2011 Apr 7.


Effects of the amino acid linkers on the melanoma-targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-MSH peptides. Full Text

Guo H, Yang J, Gallazzi F, Miao Y.

J Nucl Med. 2011 Apr;52(4):608-16. doi: 10.2967/jnumed.110.086009. Epub 2011 Mar 18.


Effect of solution viscosity on intraprotein electron transfer between the FMN and heme domains in inducible nitric oxide synthase. Full Text

Li W, Fan W, Elmore BO, Feng C.

FEBS Lett. 2011 Aug 19;585(16):2622-6. doi: 10.1016/j.febslet.2011.07.022. Epub 2011 Jul 26.


EmmdR, a new member of the MATE family of multidrug transporters, extrudes quinolones from Enterobacter cloacae. Full Text

He GX, Thorpe C, Walsh D, Crow R, Chen H, Kumar S, Varela MF.

Arch Microbiol. 2011 Oct;193(10):759-65. doi: 10.1007/s00203-011-0738-1. Epub 2011 Aug 7.


Fever from the forest: prospects for the continued emergence of sylvatic dengue virus and its impact on public health. Full Text

Vasilakis N, Cardosa J, Hanley KA, Holmes EC, Weaver SC.

Nat Rev Microbiol. 2011 Jun 13;9(7):532-41. doi: 10.1038/nrmicro2595.


Genetic complexity of fusidic acid-resistant small colony variants (SCV) in Staphylococcus aureus. Full Text

Lannergård J, Cao S, Norström T, Delgado A, Gustafson JE, Hughes D.

PLoS One. 2011;6(11):e28366. doi: 10.1371/journal.pone.0028366. Epub 2011 Nov 29.


Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation. Full Text

Siamakpour-Reihani S, Peterson TA, Bradford AM, Argiros HJ, Haas LL, Lor SN, Haulsee ZM, Spuches AM, Johnson DL,Rohrschneider LR, Shuster CB, Lyons BA.

J Mol Recognit. 2011 Mar-Apr;24(2):314-21. doi: 10.1002/jmr.1062.


Inhibitory effects of ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit and para-acylated phenols on human cancer cells. Full Text

Bryant ZE, Janser RF, Jabarkhail M, Candelaria-Lyons MS, Romero BB, Van slambrouck S, Steelant WF, Janser I.

Bioorg Med Chem Lett. 2011 Feb 1;21(3):912-5. doi: 10.1016/j.bmcl.2010.12.074. Epub 2010 Dec 19.


In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives. Full Text

Evdokimov NM, Lamoral-Theys D, Mathieu V, Andolfi A, Frolova LV, Pelly SC, van Otterlo WA, Magedov IV, Kiss R, Evidente A,Kornienko A.

Bioorg Med Chem. 2011 Dec 1;19(23):7252-61. doi: 10.1016/j.bmc.2011.09.051. Epub 2011 Oct 2.


Intraprotein electron transfer between the FMN and heme domains in endothelial nitric oxide synthase holoenzyme. Full Text

Feng C, Taiakina V, Ghosh DK, Guillemette JG, Tollin G.

Biochim Biophys Acta. 2011 Dec;1814(12):1997-2002. doi: 10.1016/j.bbapap.2011.08.004. Epub 2011 Aug 16


Markers of fibrosis and epithelial to mesenchymal transition demonstrate field cancerization in histologically normal tissue adjacent to breast tumors. Full Text

Trujillo KA, Heaphy CM, Mai M, Vargas KM, Jones AC, Vo P, Butler KS, Joste NE, Bisoffi M, Griffith JK.

Int J Cancer. 2011 Sep 15;129(6):1310-21. doi: 10.1002/ijc.25788. Epub 2011 Feb 11.


 Molecular cloning and characterization of mannitol-1-phosphate dehydrogenase from Vibrio cholerae. Full Text

Rambhatla P, Kumar S, Floyd JT, Varela MF.

J Microbiol Biotechnol. 2011 Sep;21(9):914-20.


Multicomponent Synthesis of 2,3-Dihydrochromeno[4,3-d]pyrazolo[3,4-b]pyridine-1,6-diones: A Novel Heterocyclic Scaffold with Antibacterial Activity. Full Text

Frolova LV, Malik I, Uglinskii PY, Rogelj S, Kornienko A, Magedov IV.

Tetrahedron Lett. 2011 Dec 7;52(49):6643-6645.


Mutation in the flavin mononucleotide domain modulates magnetic circular dichroism spectra of the iNOS ferric cyano complex in a substrate-specific manner. Full Text

Sempombe J, Galinato MG, Elmore BO, Fan W, Guillemette JG, Lehnert N, Kirk ML, Feng C.

norg Chem. 2011 Aug 1;50(15):6859-61. doi: 10.1021/ic200952c. Epub 2011 Jun 30.


One-pot multicomponent synthesis of diversely substituted 2-aminopyrroles. A short general synthesis of rigidins A, B, C, and D. Full Text

Frolova LV, Evdokimov NM, Hayden K, Malik I, Rogelj S, Kornienko A, Magedov IV.

Org Lett. 2011 Mar 4;13(5):1118-21. doi: 10.1021/ol103149b. Epub 2011 Jan 26.


Pulsed ENDOR determination of relative orientation of g-frame and molecular frame of imidazole-coordinated heme center of iNOS. Full Text

Astashkin AV, Fan W, Elmore BO, Guillemette JG, Feng C.

J Phys Chem A. 2011 Sep 22;115(37):10345-52. doi: 10.1021/jp204969d. Epub 2011 Aug 26.


Replacement of the 3' untranslated variable region of mosquito-borne dengue virus with that of tick-borne Langat virus does not alter vector specificity. Full Text

Tumban E, Mitzel DN, Maes NE, Hanson CT, Whitehead SS, Hanley KA.

J Gen Virol. 2011 Apr;92(Pt 4):841-8. doi: 10.1099/vir.0.026997-0. Epub 2011 Jan 7.


Role of an isoform-specific substrate access channel residue in CO ligand accessibilities of neuronal and inducible nitric oxide synthase isoforms. Full Text

Feng C, Fan W, Ghosh DK, Tollin G.

Biochim Biophys Acta. 2011 Mar;1814(3):405-8. doi: 10.1016/j.bbapap.2010.11.007. Epub 2010 Dec 10.


Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents. Full Text

Evdokimov NM, Van Slambrouck S, Heffeter P, Tu L, Le Calvé B, Lamoral-Theys D, Hooten CJ, Uglinskii PY, Rogelj S, Kiss R,Steelant WF, Berger W, Yang JJ, Bologa CG, Kornienko A, Magedov IV.

J Med Chem. 2011 Apr 14;54(7):2012-21. doi: 10.1021/jm1009428. Epub 2011 Mar 9.


SugE, a new member of the SMR family of transporters, contributes to antimicrobial resistance in Enterobacter cloacae. Full Text

He GX, Zhang C, Crow RR, Thorpe C, Chen H, Kumar S, Tsuchiya T, Varela MF.

Antimicrob Agents Chemother. 2011 Aug;55(8):3954-7. doi: 10.1128/AAC.00094-11. Epub 2011 May 16.


Synthesis and characterization of tritylthioethanamine derivatives with potent KSP inhibitory activity. Full Text

Rodriguez D, Ramesh C, Henson LH, Wilmeth L, Bryant BK, Kadavakollu S, Hirsch R, Montoya J, Howell PR, George JM,Alexander D, Johnson DL, Arterburn JB, Shuster CB.

Bioorg Med Chem. 2011 Sep 15;19(18):5446-53. doi: 10.1016/j.bmc.2011.07.054. Epub 2011 Jul 30.


Synthesis and evaluation of novel gonadotropin-releasing hormone receptor-targeting peptides. Full Text

Guo H, Lu J, Hathaway H, Royce ME, Prossnitz ER, Miao Y.

Bioconjug Chem. 2011 Aug 17;22(8):1682-9. doi: 10.1021/bc200252j. Epub 2011 Jul 20.


 Synthesis of C-1 homologues of pancratistatin and their preliminary biological evaluation. Full Text

Vshyvenko S, Scattolon J, Hudlicky T, Romero AE, Kornienko A.

Bioorg Med Chem Lett. 2011 Aug 15;21(16):4750-2. doi: 10.1016/j.bmcl.2011.06.068. Epub 2011 Jun 22.


 The double-edged sword: How evolution can make or break a live-attenuated virus vaccine. Full Text

Hanley KA.

Evolution (N Y). 2011 Dec;4(4):635-643.


The Escherichia coli DinD protein modulates RecA activity by inhibiting postsynaptic RecA filaments. Full Text

Uranga LA, Balise VD, Benally CV, Grey A, Lusetti SL.

J Biol Chem. 2011 Aug 26;286(34):29480-91. doi: 10.1074/jbc.M111.245373. Epub 2011 Jun 22.


Unprecedented C-2 arylation of indole with diazonium salts: Syntheses of 2,3-disubstituted indoles and their antimicrobial activity. Full Text

Daly S, Hayden K, Malik I, Porch N, Tang H, Rogelj S, Frolova LV, Lepthien K, Kornienko A, Magedov IV.

Bioorg Med Chem Lett. 2011 Aug 15;21(16):4720-3. doi: 10.1016/j.bmcl.2011.06.081. Epub 2011 Jun 25.