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New Mexico’s INBRE program gets renewed by the NIH to enhance Biomedical Research

New Mexico INBRE will be able to expand its efforts to increase biomedical research capability, improve understanding of disease and treatments, plus drive science growth through its statewide network, thanks to a five-year, $18.6 million grant from the National Institutes of Health.

New Mexico IDeA Networks of Biomedical Research (INBRE) is housed at New Mexico State University, and collaborates with more than 10 partner institutions across the state.  One of the goals of the funding is to continue building a nationwide, multi-disciplinary research network that will enhance the biomedical research base with lead scientists, educators and students. This grantwill also go towards promoting community engagement research, addressing health disparities in medically underserved areas and provide student research experiences through summer programs. 

The NM-INBRE conducts biomedical research in thematic research areas that include: Structure and Function of Biomolecules; Cell and Organism; Pathogens; Bioinformatics and Genomics; Community-Based Participatory Research. Projects also align with the goal of advancing clinical/translational research that have “bench to bedside” and community components, focusing on critical health problems in Brain and Behavioral Health; Cancer; Cardiovascular and Metabolic Diseases; Child Health; Environmental Health; Infectious Disease and Immunity.

This is the fourth grant renewal for the New Mexico INBRE program, which has achieved significant outcomes and impacts over the years.  Since 2001, it has funded more than 70 faculty investigators across the state, has trained more than 920 students at partner institutions and has garnered a total of $118.5 million in research funding.

For the next five years, New Mexico INBRE plans to increase the number of biomedical research projects funded, grow and sustain a competitive, biomedical research base, plus provide cohesive undergraduate and graduate training programs. 


NM-INBRE Science Advisor Dr. Vallabh “Raj” Shah has been awarded a 5-year $3.5 million grant by the NIH to study kidney cancer 

Vallabh “Raj” Shah, PhD, Distinguished and Regents’ Professor in The University of New Mexico’s Departments of Biochemistry & Molecular Biology and Internal Medicine, and Mark Unruh, MD, chair of Internal Medicine, will study risk factors for chronic kidney disease (CKD) among Native Americans in the southwestern U.S. to determine whether any progress is being made

Shah — who has worked with Native Americans for more than 25 years — and Unruh formed a consortium of investigators with extensive experience in studying chronic diseases, including diabetes and kidney disease.

The National Institutes of Health (NIH) recently announced a five-year $3.5 million grant to fund the consortium in hopes of improving the understanding of potential risk factors for CKD and cardiovascular disease progression, as well as the impact of the disease among Native Americans.  Read More


 

New Mexico INBRE investigator Dr. Kevin Houston has been awarded $1 million by the NIH

New Mexico INBRE investigator Dr. Kevin Houston has been awarded a $1 million, four-year grant from the National Institutes of Health (NIH) to investigate how GPER1-dependent mechanisms of tamoxifen action contribute to tamoxifen resistance in breast cancer cells. 

The goal of this multiyear study entitled “GPER1-Dependent Regulation of IGF-1R in Tamoxifen Treated Breast Cancer Cells” is to further characterize how GPER1 is involved in the development of tamoxifen resistance in breast cancer cells and to identify potential targets for future design of pharmaceutical treatments that can lessen the likelihood that resistance will develop in breast cancer patients that are treated with tamoxifen.

In addition, this funding will provide the resources necessary to encourage and support both undergraduate and graduate students in research training while they are completing their studies at NMSU.