INBRE News
Researchers dig deep into cancer with magnetic nanoparticles
Drugs and other treatments can be quite effective at killing cancer cells, yet many fall short as they struggle to penetrate deep into solid tumors due to physical barriers within the tissue. But in a recent study described in ACS Nano, researchers may have found...
Decreasing the invasiveness of deep brain stimulation
Study in sheep effectively modulated deep brain regions without drilling into the skull Deep brain stimulation—the application of electricity to specific deep brain regions to modulate their function—has been used clinically for over 25 years. This technique is used...
3D-printed heart tissue, imbued with solar tech, regulates heart rhythm in preclinical study
New research suggests that engineered tissues could one day do some of the work of traditional electrical stimulation devices while offering more customizable and biologically friendly solutions. A team of NIH-funded researchers produced...
Early sickle cell disease intervention may lower stroke risk
In NIBIB study, bone marrow transplantation during adolescence but not adulthood protected animal arteries Bone marrow transplantation (BMT) can potentially cure sickle cell disease, an inherited and painful blood disorder, but because of its potential drawbacks...
Mid-career academic researcher enjoys seeing the real-world impact of her work
Muyinatu Bell, Ph.D., is a mid-career scientist at Johns Hopkins University who is recognized for her innovations that have improved the quality of ultrasound and photoacoustic imaging. Read her profile on our Meet a Scientist page. Read More
Stimulating mice brains with focused ultrasound changes behavioral responses to pain
Transcranial focused ultrasound (tFUS) is a promising technique for non-invasive brain stimulation. By transmitting low-intensity ultrasound waves, tFUS can target deep brain regions with potentially greater precision than other forms of...
Portable MRI, enhanced by AI, proves viable in brain imaging for dementia
Of all the instruments in the modern medicine toolbox, magnetic resonance imaging, or MRI, is one of the most powerful. But in many regions, the expense, space, and expertise required to use it puts this tool out of reach. A new study suggests that, with a...
Seeing eye to eye: building a cost-effective tool to visualize cancer
Frugally designed system, evaluated in mice, aims to improve access to fluorescence-guided surgery Cutting-edge surgical tools are often made with state-of-the-art technology, which can limit their overall accessibility. In an effort to expand surgical options for...
Engineering a smile
NIH-funded researchers restore facial nerve function in animals with stem cell-based conduits With the help of some of nature’s best engineers, NIBIB-funded researchers have developed technology to regrow damaged facial nerves. Leveraging stem cells’ ability to create...
Building a multilayered drug delivery system that’s activated by ultrasound
NIH-funded researchers release a drug in deep brain regions of non-human primates Releasing a drug selectively in specific locations in the body, including the brain, has been challenging. Researchers at the University of Utah have tackled the problem by designing...